Also means
inflammation
Usage Note
Irritazione covers both the emotional sense ('annoyance') and the medical sense ('skin irritation'), so context usually disambiguates. In everyday speech you will often hear fastidio for mild emotional annoyance, while irritazione is slightly more formal or intense. The adjective irritante ('irritating') and verb irritare ('to irritate') share the same root.
Examples
"Quella musica ad alto volume mi provoca irritazione."
Natural Translation
That loud music causes me irritation.
Literal Translation
That music at high volume to-me causes irritation.

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